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| Blood tests may also be used to determine whether TB is active or latent (inactive), and microscopic sputum analyses or cultures can find TB bacteria in the sputum. Chest x-rays and computer tomography (CT) scans are also used to diagnose TB. If the immune system traps the TB bacteria and creates scar tissue, this tissue and the lymph nodes may harden like stone in a calcification process. This results in granuloma (rounded marble-like scars) that often appear on x-rays and CT scans. However, if these scars do not show any evidence of calcium on an x-ray, they can be difficult to distinguish from cancer. Who gets tuberculosis? Tuberculosis is spread from person to person through tiny droplets of infected sputum that travel through the air. If an infected person coughs, sneezes, shouts, or spits, bacteria can enter the air and come into contact with uninfected people who breath the bacteria into their lungs. Although anyone can become infected with TB, some people are at a higher risk, such as: Those who live with others who have active TB infections Poor or homeless people Foreign-born people who come from countries with endemic TB Older people, nursing home residents, and prison inmates Alcoholics and intravenous drug users Those who suffer from malnutrition Diabetics, cancer patients, and those with HIV/AIDS or other immune system problems Health-care workers Workers in refugee camps or shelters How is tuberculosis treated? Treatment for TB depends on the whether the disease is active of latent. If TB is in an inactive state, an antibiotic called isoniazid (INH) is prescribed for six to twelve months.
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INH is not prescribed to pregnant women, and it can cause side effects such as liver damage and peripheral neuropathy. Active TB is treated with INH as well as drugs such as rifampin, ethambutol, and pyrazinamide. It is also not uncommon for TB patients to receive streptomycin if the disease is extensive. Drug therapies for TB may last many months or even years. If a patient has a drug-resistant strain of TB, several drugs in addition to the main four are usually required. In addition, treatment is generally much longer and can require surgery to remove damaged lung tissue. The largest barrier to successful treatment is that patients tend to stop taking their medicines because they begin to feel better. It is important to finish medications in order to completely eradicate the TB bacteria from the body.
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